| Date | Location | Result | |
| Nov 13, 2021 | Edinboro, PA | Edinboro 3, Slippery Rock 0 (25-15,25-18,25-15) | Box score |
| Nov 12, 2021 | Erie, PA | Gannon 3, Slippery Rock 0 (25-13,25-18,25-14) | Box score |
| Nov 06, 2021 | Slippery Rock, PA | Indiana (PA) 3, Slippery Rock 0 (26-24,25-23,25-12) | Box score |
| Nov 05, 2021 | Slippery Rock, PA | Clarion 3, Slippery Rock 0 (25-7,25-15,25-14) | Box score |
| Oct 30, 2021 | California, PA | Cal U (PA) 3, Slippery Rock 0 (25-13,25-22,25-13) | Box score |
| Oct 26, 2021 | Greensburg, PA | Seton Hill 3, Slippery Rock 0 (25-15,25-16,25-23) | Box score |
| Oct 23, 2021 | Slippery Rock, PA | Slippery Rock 3, Kutztown 2 (25-19,25-15,22-25,19-25,16-14) | Box score |
| Oct 22, 2021 | Johnstown, PA | Pitt.-Johnstown 3, Slippery Rock 0 (25-22,25-21,25-12) | Box score |
| Oct 19, 2021 | Slippery Rock, PA | Mercyhurst 3, Slippery Rock 2 (15-25,24-26,25-16,25-15,15-9) | Box score |
| Oct 16, 2021 | Slippery Rock, PA | Gannon 3, Slippery Rock 1 (25-12,25-11,24-26,25-19) | Box score |
| Oct 15, 2021 | Slippery Rock, PA | Edinboro 3, Slippery Rock 0 (25-8,25-17,25-18) | Box score |
| Oct 09, 2021 | Clarion, PA | Clarion 3, Slippery Rock 0 (25-15,25-16,25-23) | Box score |
| Oct 08, 2021 | Indiana, PA | Indiana (PA) 3, Slippery Rock 0 (25-10,26-24,25-13) | Box score |
| Oct 05, 2021 | Slippery Rock, PA | Tiffin 3, Slippery Rock 1 (21-25,25-17,25-18,25-21) | Box score |
| Oct 02, 2021 | Slippery Rock, PA | Cal U (PA) 3, Slippery Rock 1 (25-16,25-17,22-25,25-16) | Box score |
| Oct 01, 2021 | Slippery Rock, PA | Seton Hill 3, Slippery Rock 1 (14-25,25-22,25-23,25-19) | Box score |
| Sep 24, 2021 | Erie, PA | Slippery Rock 3, Mercyhurst 0 (25-19,25-21,26-21) | Box score |
| Sep 21, 2021 | Slippery Rock, PA | Pitt.-Johnstown 3, Slippery Rock 2 (17-25,25-13,20-25,25-21,15-6) | Box score |
| Sep 18, 2021 | Wheeling, WV | Fairmont St. 3, Slippery Rock 2 (23-25,25-17,25-13,13-25,15-7) | Box score |
| Sep 18, 2021 | Wheeling, WV | Wheeling 3, Slippery Rock 0 (25-15,25-15,25-17) | Box score |
| Sep 17, 2021 | West Liberty, W.Va. | NDC 3, Slippery Rock 1 (21-25,25-14,25-17,25-16) | Box score |
| Sep 17, 2021 | West Liberty, W.Va. | Slippery Rock 3, West Liberty 2 (25-15,23-25,21-25,25-23,15-11) | Box score |
| Sep 11, 2021 | Canton, OH | Saginaw Valley 3, Slippery Rock 1 (25-17,23-25,25-16,25-11) | Box score |
| Sep 11, 2021 | Canton, OH | Fairmont St. 3, Slippery Rock 0 (25-22,25-20,25-19) | Box score |
| Sep 10, 2021 | Canton, OH | Seton Hill 3, Slippery Rock 0 (25-22,25-18,25-16) | Box score |
| Sep 10, 2021 | Canton, OH | Malone 3, Slippery Rock 2 (17-25,25-21,25-21,22-25,18-16) | Box score |
| Sep 04, 2021 | Lock Haven, PA | Slippery Rock 3, Lock Haven 2 (25-22,22-25,20-25,25-17,15-12) | Box score |
| Sep 04, 2021 | Lock Haven, PA | Slippery Rock 3, Roberts Wesleyan 0 (25-19,25-11,25-13) | Box score |
| Sep 03, 2021 | Lock Haven, PA | Malone 3, Slippery Rock 0 (25-15,25-14,25-21) | Box score |
| Sep 03, 2021 | Lock Haven, PA | Notre Dame (OH) 3, Slippery Rock 0 (28-26,25-17,25-12) | Box score |